Sabinsa, the multi-national health science company founded by Dr. Muhammed Majeed 35 years ago, announces the most recent clinical study on its branded 2.5% USP grade Ashwagandha root ingredient: Shagandha. The study, published in the journal Medicine, suggested that Shagandha can effectively reduce stress and anxiety by decreasing cortisol and increasing serotonin in healthy individuals with mild to moderate stress-related symptoms, compared to placebo.

In the 60-day double-blind, placebo-controlled study, 54 individuals were randomized and 50 completed the study. The research suggests that Sabinsa’s Shagandha (2.5% withanolides), with a 500mg once daily dose, can effectively improve stress and anxiety by reducing morning salivary cortisol levels, an indicator of stress, and increasing serotonin in healthy individuals with mild to moderate symptoms.

Ashwagandha (Withania somnifera) is one of the best-known Indian botanicals and has been used in Ayurvedic preparations since the Vedic era, dating back 3000-4000 years. In Ayurveda, ashwagandha is classified as a rasayana, meaning “rejuvenative tonic.” Traditionally it was widely used in people of all ages for a range of imbalances.

“The world’s population is living through extraordinarily stressful events, and many are turning to natural remedies to help them cope,” remarked Dr. Muhammed Majeed, the Founder and Chairman of Sabinsa Corporation. “Just as we’ve seen with Curcumin C3 Complex®, published clinical studies help both consumers and healthcare practitioners understand the safety and efficacy of standardized herbal extracts. This is just the most recent example of Sabinsa’s long history of conducting clinical studies on herbs to confirm and expand upon traditional knowledge of their benefits.”

A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study by Majeed M, Nagabhushanam K, Mundkur L. Medicine 2023;102:41(e35521).