A placebo-controlled, randomized double-blind clinical trial published in Phytotherapy Research titled Effects of Supplementation with Curcuminoids on Dyslipidemia in Obese Patients: A Randomized Crossover Trial (Mohammadi et al, 2012) reported that Sabinsa’s Curcumin C3 Complex® led to a significant reduction in serum triglycerides concentration in a randomized crossover clinical trial.
Abnormal amount of lipids in the blood is a leading risk factor for cardiovascular disease. It is also a common feature of obesity and metabolic syndrome, and precedes Alzheimer’s disease. This study investigated the lipid lowering activity of curcumin in obese individuals. Thirty participants received curcuminoids (1g/day) with natural bioavailability-enhancer BioPerine®, or placebo in a randomized, double-blind, placebo-controlled, crossover trial. Serum concentrations of total cholesterol, triglycerides, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol, together with anthropometric parameters and high-sensitivity C-reactive protein were measured before and after each treatment period.