Black pepper is a common household spice that has been used for thousands of years. Black pepper extract has also been used extensively in formulas conceived in the traditional system of medicine in India known as Ayurveda.

Bioperine is a pure piperine extract obtained from black pepper fruits that are cultivated in the damp, nutrient rich soil regions of southern India. The delicate pepper berries are hand harvested just prior to ripening and then sun dried to assure optimum maturity and quality. The extract of piperine, in the patent pending form of Bioperine, has been clinically tested in the United States and shown to significantly enhance the bioavailability of various supplemented nutrients through increased absorption.

The metabolic process that generates energy at the cellular level in our body is called thermogenesis. While thermogenesis has typically been categorized as a key factor in weight loss, to confine the scope of its function to this aspect alone is incomplete. Thermogenesis plays an integral role in our body's ability to properly utilize the daily foods and nutrients we take in. It sets in motion the mechanisms that lead to digestion and subsequent gastrointestinal absorption.

Piperine, in the patent pending form of Bioperine, enhances the body's natural thermogenic activity - hence the term Thermonutriene™. This enhancement may be explained as a means of increasing thermal energy sufficient to "power up" mechanisms related to thermogenesis. This in turn results in increased metabolic processes that create a "demand" for "supply" of a broad range of nutrients that contribute to metabolism, i.e. vitamins, minerals, herbals, amino acids, etc. It is as if Bioperine activates a metabolic paddle wheel, of sorts, that selectively provides a more efficient mode of nutrient transportation into the blood. Based on available research, piperine is unique in its thermonutrient activity.

Casual thought gives the impression that if you take more of a nutrient, more will be available for use by the body. Biologically speaking, this is not always true. Some nutrients at higher doses actually negate the benefit and absorption of other nutrients. Ideally, more from less is best. Similar reasoning could lead one to believe that if the source of Bioperine is found in black pepper, all one needs to do is increase their consumption of black pepper to achieve enhanced nutrient absorption. Again, this is not true.

Excluding disease, the window of opportunity for nutrient absorption is limited by time. If piperine were to remain captive in the form of raw black pepper, its bioavailability enhancing properties would be liberated much too late to have any effect on nutrient absorption. A purified extract of piperine is necessary for this. Based on clinical data, having Bioperine in the "right place at the right time" in the digestive tract with a supplemented nutrient results in enhanced absorption.

The subtle, yet potent properties of Bioperine have been measured in several clinical studies with healthy volunteers in the U.S. These studies measured the absorption of three distinct categories of products. The categories evaluated with and without Bioperine were fat soluble (beta-carotene), water soluble (vitamin B6) and a mineral (selenium, in the form of selenomethionine). Gastrointestinal absorption of all the studied nutrients, as measured by amounts present in the blood, increased dramatically when administered with Bioperine as compared to the control group receiving the nutrient alone. Selenium levels increased by 30%, beta-carotene increased by 60%, while the vitamin B6 increase was slightly higher than beta-carotene. All studies used Bioperine in the amount of 5 mg per dose.

The advantage of Bioperine®

Bioperine is the only source of piperine to obtain patent pending status for its ability to increase the bioavailability of nutritional compounds. Bioperine is also the only source of piperine to undergo clinical studies in the U.S. to substantiate its safety and efficacy for nutritional use.

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