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Current
Issues - Newsletter
January - February 2006
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Message from Dr. Majeed |
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Sabinsa Corporation is now in its eighteenth year. We have expanded our range of branded nutraceutical and cosmeceutical ingredients, conducted pioneering clinical research into their efficacy and safety, and built a sizeable intellectual property portfolio. |
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2006 began well for us. On January 3rd, we were granted a US Patent for a bioavailable composition of methylselenocysteine, a naturally occurring form of the essential trace mineral nutrient, selenium. Quality continues to be our major priority. We recently received certification from NSF International for yet another branded ingredient, Forslean (Sabinsa's patented, award winning Coleus forskohlii Extract).
In an industry posed with a number of regulatory challenges including the impending GMP regulations, our focus has always been on quality and application oriented research. Several standardized extracts that we manufacture and supply, are currently being used in Investigational New Drug (IND) studies in the United States and elsewhere, with approval from the concerned regulatory authorities.
To build a strong and credible image for the industry, both manufacturers of finished products, and suppliers of raw ingredients need to focus on establishing and maintaining quality standards, clinically validating ingredient health claims, and educating consumers on the health benefits of phytonutrients and nutritional materials. I stand firm in the belief that these ingredients will emerge as safe and effective measures, in preventive heath maintenance, and as adjuncts to therapeutics in the treatment of chronic diseases.
As always, we remain caring and committed to the spirit of innovation in preventive healthcare, and will continue to provide the quality ingredients that you have come to expect from SABINSA, this year and in the years to come. I take this opportunity to wish you all a very Happy and Healthy 2006 |
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SABINSA OPENS OFFICE IN GERMANY |
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Sabinsa Corporation has opened a new office in Germany, the Corporation's first office in Europe. Registered under the name Sabinsa Europe GmbH, this office in Frankfurt will coordinate Sabinsa's sales and marketing operations in Europe. |
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FORSLEAN® : NEW STUDY, AND NSF CERTIFICATION
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A study published in the December 2005 Journal of the International Society of Sports Nutrition (www.theissn.org) entitled “Effects of Coleus forskohlii extract supplementation on body composition and markers of health in sedentary overweight females” confirmed that ForsLean®, Sabinsa Corporation’s patented Coleus forskohlii extract and the only known plant source of forskolin, promotes favorable changes in body composition.
The 12-week randomized, double-blind, placebo-controlled study of 23 overweight women conducted by researchers in the Exercise & Sport Nutrition Lab at the Center for Exercise, Nutrition & Preventive Health Research at Baylor University revealed that individuals receiving ForsLean showed decreases in body mass and reported less fatigue and hunger. Additionally, no clinically significant interactions were seen in metabolic markers, blood lipids, muscle and liver enzymes, electrolytes, red cells, white cells, hormones (insulin, TSH, T3, T4), heart rate or blood pressure. Study participants were given either 250 mg of ForsLean (standardized to 10 percent diterpene forskolin) or a placebo twice daily for 12 weeks. |
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As summarized by Dr. Vladimir Badmaev, vice president of scientific and medical affairs, Sabinsa Corporation, these study results indicate that ForsLean helps preserve lean body mass, improve body composition and mitigate weight gain in overweight females with no apparent side effects.
In related news, Forslean was certified by NSF International. ForsLean underwent a rigorous toxicology review and purity testing to guarantee it is free of contaminants. Additionally, Sabinsa's facilities were previously audited and found to adhere to NSF's good manufacturing practices standards.
Sabinsa holds U.S. Patent #5,804,596 and European Patent #0977564 for the use of forskolin as a weight management and body composition ingredient and manufactures and supplies various extract strengths for use in a variety of supplements and products. Other international patents are pending. For more information visit www.forslean.com.
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CLINICAL RESEARCHERS PREFER USING SABINSA'S C3 COMPLEX
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Sabinsa Corporation's Ò was named as the curcumin ingredient of choice by M.D. Anderson Cancer Center at the University of Texas. M.D. Anderson Cancer Center is currently conducting numerous studies to determine the effects of curcumin, an extract of turmeric root, in fighting against several types of cancers.
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Dr. Bharat Aggarwal, professor of cancer research, M.D. Anderson Cancer Center stated that although there are numerous companies that supply curcumin, consumers need to be careful that they are buying the genuine product, which is why his research group recommends Curcumin C3 Complex. He also mentioned 'supercurcumin' from Sabinsa, that in addition contains BioperineÒ, a patented extract from black pepper fruits, which enhances the absorption and utilization of curcuminoids.
According to researchers at M.D. Anderson Cancer Center, curcumin blocks a key biological pathway needed for development of melanoma and other cancers. Curcumin shuts down nuclear factor-kappa B (NF-kB), a powerful master switch known to regulate expression of more than 300 genes that promote an abnormal inflammatory response that leads to a variety of disorders, including arthritis and cancer. |
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COSMETIC CORNER |
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Natural Antimicrobials and Preservatives |
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Recent trends in personal care heighten the need for an "all natural" ingredient listing on product labels. Formulators therefore seek natural alternatives to replace conventionally used functional ingredients. Driven by regulatory issues and safety concerns, synthetic ingredients are now subject to increasing scrutiny worldwide. The quest for natural antimicrobials and preservatives has become an area of dynamic research in personal care, particularly in view of the increased incidence of "antibiotic resistance", arising from non-judicious use of conventional antibiotics.
Research trends in personal care now feature natural antimicrobial ingredients that help to retard the growth of topical pathogens, as well as natural preservatives that retard the growth of microbes in finished personal care product formulations. Multifunctionality is an additional advantage of natural extracts used as antimicrobials. Several of them offer anti-inflammatory, immunological and wound healing support as well. Although no single natural extract has been found to be comparable in efficacy to conventionally used preservatives such as parabens, combinations of naturals with synergistic activity have been identified to offer protection against invasive growth of bacteria and fungi. Such extracts also offer antioxidant action, and other benefits with beneficial effects on product shelf life.
Sabinsa Corporation offers several such ingredients including essential oils
such as Coleus forskohlii oil and Turmeric oil, plant extracts such as Rosemary extract, Rosmarinic acid, Tetrahydrocurcuminoids, Galanga Extract, Green tea Extract, Ursolic acid, Oleanolic acid, SapindinÒ, Oleuropein, Neem oil limonoids, Policosanol and specialty chemicals such as 1,2 hexanediol. |
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TRADE SHOWS |
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INFORMEX 2006, Orlando, Florida, Feb 14th-17th, Stand # 369
TeamWorks - Midwest SCC Show (March 29)
NutraCon/SupplySide west: March 20-22. |
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PRODUCT ADS |
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Look for Sabinsa product advertisements in the following trade publications:
CTFA Buyer's guide, CTMW, HAPPI, Cosmetics &Toiletries, GCI, Soap Perfumery & Cosmetics, Chemical Market Reporter, Natural Products Insider, Nutritional Outlook, Functional Foods & Nutraceuticals |
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Our Additional Product Websites |
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