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Current
Issues - Newsletter
May-June 2000 |
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Fiber
Helps Diabetics Control Blood Sugar- US Study |
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According
to a recent randomized, crossover study published in
the New England Journal of Medicine, a diet high in
fiber, particularly of the soluble type, can give Type
2 diabetics better control of their blood sugar levels
and also reduce their cholesterol levels.1
Thirteen Type 2 diabetics participated in the study.
The subjects followed two diets each for a period of
six weeks. For one six week period, the subjects received
a diet containing a moderate amount of fiber (total
fiber = 24 g consisting of 8 g soluble fiber and 16
g insoluble fiber), which is the fiber intake recommended
by the American Diabetes Association (ADA). For the
other six week period, the subjects received a high-fiber
diet (total fiber = 50 g consisiting of 25 g soluble
fiber and 25 g insoluble fiber). None of the foods the
subjects consumed were fortified with fiber.
Comparison of the high-fiber and ADA diet during the
sixth week of administration revealed the following
results in favor of the high-fiber diet:
- Mean daily preprandial plasma glucose concentrations
were 13 mg/dL lower.
- The high-fiber diet lowered the area under the curve
for 24-hour plasma glucose concentrations by 10% (p
= 0.02).
- The area under the curve for 24-hour plasma insulin
concentrations were 12% (p = 0.05) lower.
- Plasma concentrations for total cholesterol, triglycerides,
and very low density lipoprotein (VLDL) cholesterol
were reduced 6.7% (p = 0.02), 10.2% (p = 0.02), and
12.5% (p = 0.01), respectively.
In an editorial that appears in the same journal issue
as the study, Dr. Marc Rendell of the Creighton Diabetes
Center in Omaha, Nebraska commented that the improvements
in the subjects eating a high-fiber diet were similar
to what patients would observe if they took an anti-diabetes
drug.2
- Chandalia, M.; Garg, A.; Lutjohann, D.; von Bergmann,
K; Grundy, S.M.; and Brinkley, L.J. (2000) Beneficial
effects of high dietary fiber intake in patients with
type 2 diabetes mellitus. N. Engl. J. Med. 342(19),
1392-8.
- Rendell, M. (2000) Dietary treatment of diabetes
mellitus. N. Engl. J. Med. 342(19), 1440-1.
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The Importance of Fiber Digestibility
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Typically,
most Americans consume 17 g of fiber per day, and they
are reluctant to increase their fiber intake in spite
of the positive health benefits because of the known bloating
and gastrointestinal discomfort associated with increased
fiber ingestion.
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The extent of discomfort
has been determined to depend on the type of fiber,
suggesting the need to strike a balance between
digestibility and fiber functionality.
Functionality is dependent on the bulk of a fiber.
In turn, fibers with low digestibility possess
better functionality. In contrast, broken down
fiber supplements are not functional and produce
sugars that are fermented by the intestinal flora
to cause acid production, gas and bloating.
Sabinsa Corporation supplies Fenufibers®,
a fiber product obtained from fenugreek (Trigonella
foenum graecum) that contains a minimum of 50%
fiber. |
A study1 performed at the
University of Georgia evaluated the ability of the human
colonic bacterium Bacteroides ovatus V975 to ferment
Fenufibers® (fenugreek
fiber), Metamucil® (psyllium
husk), and Wheat Chex (wheat bran). As shown in Figure
1, there was little change in in vitro dry matter disapperance
(IVDMD), a measure of fiber digestibility, after 24
or 48 hours for Fenufibers®,
Metamucil®, and Wheat
Chex.

The lack of extensive fermentation
by B. ovatus V975 indicates that Fenufibers®
is a minimally digested fiber-rich supplement that can
be incorporated into soups and other food preparations,
providing the beneficial effects of fiber.
- Al-Khaldi, S.F., Martin, S.A., and Prakash, L. (1999)
Fermentation of fenugreek fiber, psyllium husk, and
wheat bran by Bacteroides ovatus V975. Current Microbiology,
39, 231-232.
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FDA Alert:
The Herb Family Aristolochia |
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The
FDA of the United States has issued an alert to doctors
to be on the lookout for botanicals from the herb family,
Aristolochia. Herbs from this family contain or may be
contaminated with an ingredient called aristolochic acid
that is toxic to the kidneys and is suspected of causing
cancer. Although no Americans have been reported to
be injured by any of the Aristolochia botanicals, the
U.S. FDA has issued the warning and is preparing to
block the import of aristolochic acid-containing herbs
based on 2 cases of kidney failure reported in Britain
and 70 cases reported in Belgium.
For a list of plants under concern, check the FDA’s
internet site located at the following address: http://www.fda.gov/opacom/hpwhats.html
and click on "dietary supplements".
- AP WorldStream via COMTEX (Washington,
June 2, 2000)
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Reduce
motion sickness with Ginger |
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Motion sickness, commonly called
travel sickness, occurs when the balance organs
in the inner air are overstimulated by repeated
small changes in the body’s position or
under conditions where visual contact with the
outside horizon are lost. Symptoms include nausea,
headache, and tiredness which may progress to
vomiting. Conditions that commonly lead to motion
sickness include travel in rough seas, turbulent
flights, and bumpy drives.
Recently, researchers at the Digestive
Disease Week meetings held in San Diego have
reported that ginger is effective in reducing
the nausea associated with motion sickness.
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Ginger has been traditionally used in China to alleviate
nausea, and Dr. Wei Ming Sun and colleagues from the
University of Michigan in Ann Arbor proved this in their
clinical study.
Wei and coworkers induced motion sickness in 7 healthy
subjects, aged 18 to 35 years, by spinning them in a
large drum for 30 minutes after they ate. Each participant
received either 1,000 mg ginger powder or a placebo
pill one hour before motion sickness was induced.
At the end of the experiment, the following findings
were reported:
- Nausea scores during the drum rotation, rated on
a scale from 1 to 3, were significantly lower for
the group that received ginger powder (average ginger
group score = 1.0) than for the control group (average
placebo group score = 2.5).
- Nausea scores after the drum rotation, rated on
a scale of 1 to 10, were also in favor of the ginger
group subjects (average nausea score for ginger group
= 1.5; average nausea score for placebo group = 7.8).
- Subjects who took ginger experienced a greater delay
in developing nausea compared to those of the control
group (11.4 minutes for the ginger group compared
to 4.6 minutes for the control group).
The authors have attributed ginger’s effectiveness
in reducing motion sickness to its ability to normalize
the rate at which the stomach contracts during accelerations
of movement. Through electrical activity measurements,
it was determined that ginger kept the rate of stomach
contractions normal during drum rotation, while subjects
who took the placebo experienced a 7% increase in stomach
contractions.
Ginger appears to be an effective herbal alternative
to the conventional antihistamine drugs used to treat
motion sickness that cause significant side effects,
such as dizziness and dry mouth.
- Reuters Health
Sabinsa Corporation supplies ginger extracts, Ginger
Dry Extract standardized for a minimum of 5% gingerols
and Ginger Soft Extract standardized for a minimum
of 20% gingerols.
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Sabinsa
Corporation Participates in IFT Food Expo |
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Sabinsa
Corporation participated in the Annual Institute of Food
Technologists (IFT) Food Expo held in Dallas, Texas June
10-14, 2000. Products from the newly introduced Functional
Food Ingredients Line were displayed.
Sabinsa’s Functional Food Ingredients Line* is
divided into 5 categories as shown below:
NUTRACEUTICALS
- Bioperine®:
a standardized extract from the fruits of Piper nigrum
L. (black pepper) that functions as a nutrient bioavailability
enhancer, increases gastrointestinal absorption of
vitamins, minerals, phytonutrients, and amino acids
- Citrin®
Products: standardized extracts from the rind
of the fruit Garcinia cambogia (Brindall berry, Malabar
tamarind) that are useful in weight management
- DigeZyme®:
a multi-enzyme blend containing amylases, proteases,
lipase, and lactase that aid in digestion
- Fenufibers®:
a standardized extract from the seeds of Trigonella
foenum-graecum (Fenugreek) that supplies dietary fiber
(see cover story)
- Fenusterols®:
a standardized extract from the seeds of Trigonella
foenum-graecum(Fenugreek) that supplies steroidal
saponins that are useful in sports nutrition and healthy
chlolesterol management
- Green Tea Extracts (40% &
75%): standardized extracts from the leaves
of Camellia sinensis that can be used as natural antioxidants
- Lactospore®:
a sporiferous preparation of Lactobacillus sporogenes
that can be used as a probiotic functional food additive
in dry food products
- Rosemary Extract: a standardized
extract from the leaves of Rosmarinus officinalis
that can be used as an antioxidant/anti-inflammatory
food agent
- Tetrahydrocurcuminoids (THC):
a color-free standardized extract from the roots of
the Curcuma longa (Turmeric) plant that may be used
as a food antioxidant (U.S. Patent# 5,861,415 granted
for curcuminoids and its derivatives, Patent pending
for composition and use)
- Ursolic acid: a standardized
powder extracted from Rosemary leaves that can be
used as a food antioxidant.
ORGANIC MINERAL SUPPLEMENTS (essential
trace elements)
- BGOV Complex: a stable,
bioavailable form of vanadium complexed with the amino
acid, glycine, that can be used as a nutritional source
of vanadium and for blood sugar management
- Chromium Polynicotinate:
an organically complexed chromium mineral supplement
- Copper Lysinate: an organic
complex of copper with the essential amino acid lysine
- L-(+)-Selenomethionine (pure):
a fully complexed L-(+)-Selenomethionine compound
that provides a minimum of 400,000 mcg elemental selenium
(40%) per gram
- Magnesium, Potassium and Calcium
Supplements: K/Mg Aspartate (Mg/K Aspartate),
Calcium Citrate, Magnesium citrate, Magnesium Aspartate,
and Calcium Aspartate
- Zinc Supplements: Zinc
Monomethionine, Zinc Magnesium Aspartate, and Zinc
Aspartate
MICRONUTRIENT PREMIXES
- Custom premixes of Vitamin blends, Vitamin/Mineral
blends, Vitamin/Antioxidant blends, Vitamin/Mineral/Antioxidant
blends, Mineral/Antioxidant blends, and Mineral blends
SPICES, SPICE OILS, & EXTRACTS
- Spice Oils, Pastes, and Oleoresins:
(e.g. Black pepper oil, Ginger oil, Garlic oil, Green
chilli oleoresin etc.)
- Spice Essential Oils:
(e.g. Black pepper oil, Cardamon oil, Mace oil etc.)
NATURAL FOOD COLORS
- Citrin®
Crystals (Anthocyanins): a standardized extract
from the fruits of the Garcinia indica tree that provides
a bright pink color and is useful in dietetic formulations
for weight management
- Curcumin 95% (Curcumin C3 Complex®):
obtained from the roots of the Curcuma longa (Turmeric)
plant
- Marigold Oleoresin: extracted
from Tagetes erecta
- Paprika Oleoresin: derived
from the dried ripe fruits of Capsicum annum (Cayenne
pepper)
- Turmeric Oleoresin: obtained
from the roots of the Curcuma longa (Turmeric) plant
which contains volatile oil, resin and yellow coloring
matter (curcuminoids)
These statements have not been evaluated by the Food
and Drug Administration. These products are not intended
to diagnose, treat, cure or prevent any disease. |
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Sabinsa's
upcoming shows |
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Sabinsa
Corporation will participate in the following Trade Show
Events in July-Sept. 2000. July 27-29, 2000:
NNFA at the Las Vegas Convention Center (Las Vegas,
NV)
Booth# 1514
Sept. 20-22, 2000:
Health Ingredients (HI) Japan with SAMI Labs Ltd. at
the Big Sight Convention Center (Tokyo, Japan) |
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| "The information
presented in the "Current Issues" Newsletter
from Sabinsa Corporation is for informational purposes
only. It is abstracted from web and print media
sources. Readers are advised to refer to the original
sources for additional information". |
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