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Current
Issues - Newsletter
January 1998 |
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Gugulipid®:
Importance of Proper Standardization
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Gugulipid®,
a registered trademark of Sabinsa Corporation, is the
standardized extract of the oleoresin of Commiphora mukul,
an Indian medicinal plant. The resin is a mixture of diterpenes,
sterols, steroids, esters and higher alcohols. The active
ingredients responsible for the well-known hypolipidemic
effects of the plant are the guggulsterones, specifically
guggulsterone E and guggulsterone Z. When purchasing
guggul products, it is vital that the extract be assessed
for purity and appropriate standardization. Sabinsa's
product Gugulipid® is
purified and standardized to contain a minimum of 2.5%
guggulsterones E and Z (the Indian pharmacopeia (IP)
limits the maximum level of guggtulsterones to not more
than 6.0%).
It is probable that guggul products which claim an
active ingredient level in excess of 6.0% may be crude
and unpurified extracts. In clinical studies, the administration
of crude (unpurified) guggul caused mild side effects
such as skin rashes, diarrhea and irregular menstruation.
There are no reports of these undesirable effects with
the purified and appropriately standardized extract.
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New Product: Fenusterols™ |
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Sabinsa
Corporation will shortly introduce to the marketplace
another new product derived from Fenugreek (Trigonella
foenum-graecum). The product, Fenusterols™ is
an extract obtained from defatted fenugreek seeds
and is standardized to contain a minimum of 50% steroidal
saponins. These saponins are also known as furostanol
saponins.
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General Structure of a
Furostanol Saponin
The principal furostanol saponin in Fenugreek
is diosgenin. Diosgenin has been proven to
have various effects on cholesterol metabolism,
specifically in lowering LDL plasma cholesterol
levels. Other furostanols in fenugreek include
gitogenin, tigogenin, smilagenin, sarsasaponin,
etc.
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| In light of the effect
which furostanol saponins exert on appetite stimulation
and hormone release, Fenusterols™ may be
potentially useful in Sports Nutrition. Fenugreek
seeds are traditionally used in appetite stimulation
the resulting increase in food intake ultimately
triggers anabolism. Animal model studies have
revealed that the furostanol saponin fraction
is responsible for the anabolic effects of fenugreek
seeds.
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addition, the furostanol class of plant steroids
have pronounced immunostimulating and luteinizing
hormone (LH) releasing properties. LH in turn
signals the pituitary gland to produce more
testosterone and high testosterone levels have
been correlated with improved athletic performance.
The mechanism of hormone releasing action of
furostanols is linked to the conversion of cholesterol
into active hormones, resulting in the simultaneous
reduction of plasma cholesterol levels.
Please call Sabinsa Corporation for further
information and samples.
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Kavita Subramanian : Marketing Executive
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Kavita joined Sabinsa Corporation last year
and has quickly become the heart and soul of
the Customer Service and Marketing Department.
Kavita received her Masters degree in Politics
from the University of Delhi, India and subsequently
worked as Guest Relations Officer in an international
hotel wherein she gathered extensive customer
service experience and the flair for international
communication.
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At Sabinsa, Kavita interacts with
a wide range of customers. She assists customers in finding
the specific products they require, helps to schedule
their shipments and informs the customers of any new and
upcoming products. She enjoys working with people and
believes that a smile goes a long way with customers.
At home, Kavita likes to unwind
by practicing her classical dancing. Kavita has also
been a professional classical dancer, with stage performances
in India, France and Japan. |
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Check
out the Sabinsa Website! |
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Sabinsa
is now accessible on the internet. Our website can be
contacted at www.sabinsa.com and has information on
products and staff, as well as back issues of the Sabinsa
Newsletter. We also have a visitor Guest Book, so please
leave your name and any comments you may have. We are
always interested in your feedback! |
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Sabins's
Globaltrek with Ayurveda |
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On
December 20th 1997, Dr. Muhammed Majeed (President of
Sabinsa) was privileged to be invited to give a presentation
on "Innovative Phytochemicals and Fine Chemicals"
at the 49th Indian Pharmaceutical Congress held in Trivandrum,
India. The Souvenir Magazine prepared for this meeting
featured an article entitled "Ayurveda and Indo-Tibetan
Materia Medica: Alternative Medicine Goes Mainstream
for Better Health Care Delivery" written jointly
by Dr. Majeed and Dr. Vladimir Badmaev. Copies of this
article are available at this website at http://www.sabinsa.com/products/ayurveda_paper.htm
and printed copies may be obtained by contacting Sabinsa.
This month, Dr. Badmaev heads to Russia
to reintroduce the Badmaev line of products to his
native country. We wish him a safe and productive
visit!
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| "The information
presented in the "Current Issues" Newsletter
from Sabinsa Corporation is for informational purposes
only. It is abstracted from web and print media
sources. Readers are advised to refer to the original
sources for additional information". |
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