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Current
Issues - Newsletter
April 1998 |
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Sabinsa
Corporation at the Tokyo Health Industry Show
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In
late March, Sabinsa Corporation along with Twinlab, GNC,
Nature's Way, Capsugel and a handful of other dietary
supplement leaders joined together in exhibiting at the
Tokyo Health Industry show in Tokyo, Japan. Mr. Gregory
Loose, Commercial attache for the U.S. embassy in Japan
stated best the objective of having a USA booth at the
show when he said "... the Embassy will be using
the exhibition and seminars at the Show to hammer home
the message of why liberalization of these products is
important for the health and welfare or the people of
Japan, as well as to showcase products and market development
in the United States ... this is the second largest market
in the world, and with the population aging faster than
any other in the developed world, the promotion of health
(including through dietary supplements) must inevitably
become a top priority."
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Left -
Todd Norton, Executive Vice President, Sabinsa
Corporation;
Middle - Loren Israelsen,
Executive Director, Utah Natural Products Alliance;
Right - Jeffrey Morrison,
President, American Herbal Products Association. |
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Ayurvedic Gems : Picrorhiza kurroa |
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Picrorhiza
kurroa (fam. Scrophulariaceae) has been used in the
traditional Indian systems of medicine to treat liver
troubles and bronchial problems.
Kutkin, a mixture of the iridoid
glycosides picroside I and kutkoside has been found
to be an efficient liver protectant, which is more
effective than silymarin obtained from milk thistle1.
Androsin, a phenolic glycoside
isolated from P. kurroa, has been attributed with
anti-asthmatic properties, probably through the
inhibition of the platelet activating factor, which
is responsible for bronchial obstruction2.
P. kurroa extracts have also been shown to possess
anti-allergic activity through mast cell stabilization3.
In a clinical study performed on 20 asthma patients,
a crude extract of P. kurroa produced significant
improvement. Interestingly, patients who had a known
history of allergy to certain food items developed
tolerance to these items during the treatment.
Sabinsa Corporation's Picroliv®
is standardized for 4% kutkin.
Ref:
1. Planta Medica.
1991, 57: 29-33.
2. Int. Arch.
Allergy Appl.Immunol., 1991. 95:128-133.
3. Aspects of Allergy
Appl. Immunnol., 1977, 11 : 137-144.
4.
Bombay Hosp. J., 1982, 24(2): 15-18.
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Bioperine®: Bioavailability
enhancer
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The
1996 patent awarded by the U.S. Patent & Trademark
Office to Sabinsa Corporation on the use of the trade
marked extract of black pepper, Bioperine®
(containing at least 95% piperine) has been much in
the news recently, on account of misinformation generated
by oleoresin maufacturers who tried to sell the product
for its patented use. Critics have made a totally false
accusation that the patent interferes with the export
of black pepper and its products from India.
The patent refers to the
USE OF PIPERINE, specifically to increase the bioavallability
of compounds such as vitamins, amino acids and minerals
in nutritional supplement formulations. It is not a
product patent and does not infringe upon the export
of black pepper, piperine or pepper oleoresin from India,
Indonesia or Sri Lanka. Based on documented research
and detailed clinical studies, the patent only serves
to render credibility to the use of a piperine as an
enhancer of nutrient bioavailability.
A recent study further
validates the use of Bioperine®
in enhancing bioavailability of nutrients by improving
absorption and altering their disposition. The in vivo
utility of curcumin, a valuable antioxidant phytonutrient,
is sometimes hampered by its poor bioavailability due
to rapid metabolism in the intestinal wall.
Concomitant administration
of piperine with curcumin (5 mg Bioperine®
/500 mg curcuminoids) to human volunteers resulted in
a significant increase in serum levels of curcumin for
a short post-administration period (1-2 hours), as compared
to controls receiving curcumin alone, and decreased
its elimination half life. The increase in bioavailability
of curcumin in the 0.25 hour to 1 hour post-administration
period with piperine was 2000% . The authors of this
study concluded that in the dosages used, piperine enhances
the serum concentration, extent of absorption and bioavailability
of curcumin, with no adverse effects (Planta Medica
64 (1998), 1-4). The study was conducted at St. John's
Medical College, Bangalore, with funding from Sami Chemical
& Extracts Ltd., Bangalore, India- a Sabinsa Company. |
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Judy
lewicki : Customer Service Associate |
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Judy
Lewicki, is a recent addition to Sabinsa's talented
marketing team. She received a B.S. degree in
Nutritional Sciences from Cook College, Rutgers
University, In 1997. Her work experience with
the New Jersey State Park Services helped her
gather valuable customer service skills. With
her sound technical background, and interest
in working with people, Judy enjoys helping
customers find the products and information
they need. We take this opportunity to welcome
Judy aboard! |
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| "The information
presented in the "Current Issues" Newsletter
from Sabinsa Corporation is for informational purposes
only. It is abstracted from web and print media
sources. Readers are advised to refer to the original
sources for additional information". |
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